Figure 5. Distribution of somatic mutations versus drivers across genomic samples.

(A) Relative density plots of mutations and declared drivers. Pie charts summarize counts per genomic sample in each of the ten cohorts (height: average number of reported mutations per sample; width: number of samples in the cohort). (B) Overlap between the predictions by MutSet&PathReg and the merge of alternative gene sets (1434 genes in total) color by Jaccard index (sets’ intersection divided with sets’ union). The MGS sizes (regardless of driver status) are expressed as marker size. Gaussian noise was added to marker coordinates for better readability.