Table 1.
The significantly differential enrichment pathways between the SSc without PAH and SSc-PAH groups.
| Gene set name | NES | NOM p-value |
|---|---|---|
| KEGG_RIBOSOME | 1.65 | 0.046 |
| KEGG_SPLICEOSOME | 1.53 | 0.002 |
| KEGG_RNA_DEGRADATION | 1.48 | 0.006 |
| KEGG_RNA_POLYMERASE | 1.43 | 0.04 |
| KEGG_BASAL_TRANSCRIPTION_FACTORS | 1.42 | 0.036 |
| KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | −1.88 | 0 |
| KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | −1.85 | 0 |
| KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS | −1.63 | 0.013 |
| KEGG_LINOLEIC_ACID_METABOLISM | −1.61 | 0.037 |
| KEGG_ARACHIDONIC_ACID_METABOLISM | −1.47 | 0.044 |