Table 2.
Subgroup analysis of lipid profiles differences between non-hypertension and hypertension according to age, BMI, and ALT*.
| Non-hypertension | Hypertension | p-value | Non-hypertension | Hypertension | p-value | |
|---|---|---|---|---|---|---|
| Age | <60 years | ≥60 years | ||||
| TC (mg/dl) | 180.93 (159.30–203.35) | 189.43 (166.23–212.63) | <0.001 | 188.66 (166.24–212.63) | 192.14 (169.72–215.92) | <0.001 |
| TG (mg/dl) | 97.46 (67.34–147.96) | 97.46 (66.45–146.19) | 0.211 | 97.46 (67.34–147.30) | 97.46 (66.45–147.08) | 0.864 |
| LDL (mg/dl) | 104 (88.53–121.39) | 108.25 (92.01–126.03) | <0.001 | 109.41 (92.78–127.2) | 110.57 (94.72–128.93) | 0.005 |
| HDL-c (mg/dl) | 49.1 (42.14–56.44) | 49.1 (42.14–56.83) | 0.242 | 49.1 (42.14–57.22) | 49.48 (42.53–57.22) | 0.741 |
| Non-HDL-c (mg/dl) | 130.28 (110.18–153.77) | 138.4 (117.14–161.6) | <0.001 | 138.02 (116.37–161.6) | 140.72 (120.23–163.92) | <0.001 |
| BMI | <23 kg/m2 | ≥23 kg/m2 | ||||
| TC (mg/dl) | 173.97 (154.64–196.39) | 181.9 (162.27–204.9) | <0.001 | 185.95 (164.69–209.15) | 191.75 (169.72–214.56) | <0.001 |
| TG (mg/dl) | 97.46 (67.34–147.96) | 97.46 (66.45–148.95) | 0.967 | 97.46 (67.34–147.96) | 97.46 (66.45–146.19) | 0.221 |
| LDL (mg/dl) | 99.74 (85.05–116.37) | 104.77 (88.90–122.17) | <0.001 | 107.86 (91.62–125.26) | 110.18 (93.94–127.96) | <0.001 |
| HDL-c (mg/dl) | 51.42 (44.85–59.15) | 52.58 (45.23–60.31) | <0.001 | 47.55 (40.98–54.9) | 48.33 (41.75–56.06) | <0.001 |
| Non-HDL-c (mg/dl) | 121.0 (103.22–142.66) | 128.74 (109.02–151.55) | <0.001 | 137.24 (116.37–160.05) | 141.5 (121.0–164.69) | <0.001 |
| ALT | <40 U/L | ≥40 U/L | ||||
| TC (mg/dl) | 179.77 (158.51–201.81) | 188.27 (166.24–211.08) | <0.001 | 192.14 (169.81–216.11) | 196.39 (173.97–220.36) | <0.001 |
| TG (mg/dl) | 97.46 (67.34–148.18) | 97.46 (66.45–147.08) | 0.123 | 97.46 (67.34–145.30) | 97.46 (70.0–145.30) | 0.2573 |
| LDL (mg/dl) | 103.61 (88.14–120.62) | 108.25 (92.01–125.65) | <0.001 | 110.95 (94.33–129.51) | 112.89 (95.49–131.83) | 0.001 |
| HDL-c (mg/dl) | 49.48 (42.53–56.83) | 49.48 (42.91–57.22) | 0.09 | 46.78 (40.21–54.12) | 47.55 (40.59–55.28) | 0.006 |
| Non-HDL-c (mg/dl) | 128.74 (109.02–151.55) | 137.24 (116.37–160.05) | <0.001 | 143.82 (121.78–168.17) | 146.71 (126.03–171.17) | <0.001 |
*
Continuous data are expressed as median (interquartile range) due to the skewed distribution.
TG, triglycerides; TC, total cholesterol; HDL-c, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, Body mass index.