Table 3.
Multivariable logistic regression model evaluating the association between lipid levels and hypertension incidence.
| Crude Model | Model 1 | Model 2 | Model 3 | |||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
| TG | ||||||||
| Q 1 (≤67.34 mg/dl) | Ref | Ref | Ref | Ref | ||||
| Q 2 (67.34–97.46 mg/dl) | 0.988 (0.933–1.046) | 0.668 | 0.985 (0.928–1.045) | 0.622 | 0.983 (0.925–1.044) | 0.577 | 0.985 (0.926–1.048) | 0.637 |
| Q 3 (97.46–147.96 mg/dl) | 0.988 (0.934–1.044) | 0.662 | 0.987 (0.931–1.046) | 0.651 | 0.983 (0.926–1.042) | 0.559 | 0.989 (0.931–1.050) | 0.711 |
| Q 4 (≥147.96 mg/dl) | 0.974 (0.921–1.031) | 0.364 | 0.974 (0.918–1.032) | 0.372 | 0.978 (0.921–1.038) | 0.457 | 0.987 (0.929–1.049) | 0.680 |
| Per 1 mg/dl increase | 1.000 (1.000–1.000) | 0.407 | 1.000 (1.000–1.000) | 0.416 | 1.000 (1.000–1.000) | 0.691 | 1.000 (1.000–1.000) | 0.905 |
| p for trend | 0.39 | 0.406 | 0.474 | 0.717 | ||||
| TC | ||||||||
| Q 1 (≤161.98 mg/dl) | Ref | Ref | Ref | Ref | ||||
| Q 2 (161.98–182.86 mg/dl) | 1.291 (1.215–1.372) | <0.001 | 1.188 (1.115–1.265) | <0.001 | 1.10 (1.031–1.173) | 0.004 | 1.097 (1.027–1.172) | 0.006 |
| Q 3 (182.86–206.44 mg/dl) | 1.510 (1.422–1.602) | <0.001 | 1.305 (1.227–1.388) | <0.001 | 1.150 (1.079–1.225) | <0.001 | 1.134 (1.063–1.209) | <0.001 |
| Q 4 (≥206.44 mg/dl) | 1.838 (1.734–1.948) | <0.001 | 1.438 (1.353–1.528) | <0.001 | 1.195 (1.123–1.272) | <0.001 | 1.159 (1.088–1.235) | <0.001 |
| Per 1 mg/dl increase | 1.007 (1.006–1.008) | <0.001 | 1.004 (1.003–1.005) | <0.001 | 1.002 (1.001–1.003) | <0.001 | 1.002 (1.001–1.003) | <0.001 |
| p for trend | <0.001 | <0.001 | <0.001 | <0.001 | ||||
| LDL | ||||||||
| Q 1 (≤89.69 mg/dl) | Ref | Ref | Ref | Ref | ||||
| Q 2 (89.69–105.54 mg/dl) | 1.158 (1.091–1.230) | <0.001 | 1.078 (1.013–1.147) | 0.018 | 1.014 (0.852–1.081) | 0.660 | 1.007 (0.944–1.074) | 0.830 |
| Q 3 (105.54–123.33 mg/dl) | 1.340 (1.265–1.421) | <0.001 | 1.185 (1.116–1.259) | <0.001 | 1.069 (1.005–1.137) | 0.035 | 1.06 (0.995–1.129) | 0.07 |
| Q 4 (≥123.33 mg/dl) | 1.540 (1.453–1.631) | <0.001 | 1.250 (1.177–1.327) | <0.001 | 1.074 (1.010–1.142) | 0.024 | 1.051 (0.987–1.119) | 0.121 |
| Per 1 mg/dl increase | 1.006 (1.005–1.007) | <0.001 | 1.003 (1.002–1.004) | <0.001 | 1.001 (1.000–1.002) | 0.007 | 1.001 (1.000–1.002) | 0.057 |
| p for trend | <0.001 | <0.001 | 0.007 | 0.049 | ||||
| HDL-c | ||||||||
| Q 1 (≤42.14 mg/dl) | Ref | Ref | Ref | Ref | ||||
| Q 2 (42.14–49.1 mg/dl) | 0.994 (0.939–1.052) | 0.833 | 1.016 (0.958–1.077) | 0.599 | 1.114 (1.074–1.212) | <0.001 | 1.097 (1.027–1.172) | <0.001 |
| Q 3 (49.1–56.44 mg/dl) | 0.984 (0.929–1.043) | 0.587 | 1.023 (0.964–1.086) | 0.455 | 1.230 (1.156–1.308) | <0.001 | 1.134 (1.063–1.209) | <0.001 |
| Q 4 (≥56.44 mg/dl) | 1.057 (0.999–1.117) | 0.053 | 1.043 (0.985–1.106) | 0.151 | 1.359 (1.279–1.443) | <0.001 | 1.159 (1.088–1.235) | <0.001 |
| Per 1 mg/dl increase | 1.002 (1.001–1.004) | 0.032 | 1.001 (0.999–1.003) | 0.331 | 1.011 (1.009–1.013) | <0.001 | 1.002 (1.001–1.003) | <0.001 |
| p for trend | 0.075 | 0.15 | <0.001 | <0.001 | ||||
| Non-HDL-c | ||||||||
| Q 1 (≤112.11 mg/dl) | Ref | Ref | Ref | Ref | ||||
| Q 2 (112.11–132.6 mg/dl) | 1.288 (1.211–1.370) | <0.001 | 1.174 (1.102–1.252) | <0.001 | 1.047 (0.981–1.118) | 0.165 | 1.044 (0.977–1.115) | 0.202 |
| Q 3 (132.6–156.19 mg/dl) | 1.548 (1.459–1.643) | <0.001 | 1.314 (1.235–1.398) | <0.001 | 1.082 (1.016–1.153) | 0.15 | 1.069 (1.002–1.140) | 0.44 |
| Q 4 (≥156.19 mg/dl) | 1.853 (1.748–1.965) | <0.001 | 1.457 (1.371–1.549) | <0.001 | 1.105 (1.037–1.177) | 0.002 | 1.080 (1.012–1.152) | 0.020 |
| Per 1 mg/dl increase | 1.007 (1.006–1.008) | <0.001 | 1.004 (1.003–1.005) | <0.001 | 1.001 (1.000–1.002) | <0.001 | 1.001 (1.000–1.002) | 0.010 |
| p for trend | <0.001 | <0.001 | 0.001 | 0.018 | ||||
OR, odds ratio; CI, confidence interval; Q, quartile. Model 1 adjust age. Model 2 adjust age and BMI. Model 3 adjust Model 2+ FPG (mmol/L), ALT(U/L), BUN, Scr, smoking status (current smoker or not), drinking status (current drinker or not), family history of diabetes (Yes or No).