Table 3.
Microbiological evaluation in the Acacia and placebo groups.
| Investigation | Acacia group (n = 33) | p value | Placebo group (n = 33) | p value | ||
|---|---|---|---|---|---|---|
| Day 0 | Day 11–14 | Day 0 | Day 11-14 | |||
| Amsel's criteria | ||||||
| Whiff test | 0.02 | 1.00 | ||||
| Negative | 24 (72.72) | 31 (93.93) | 25 (75.75) | 25 (75.75) | ||
| Positive | 9 (27.27) | 2 (6.06) | 8 (24.24) | 8 (24.24) | ||
| Clue cells | 0.02 | 1 | ||||
| Negative | 24 (72.72) | 31 (93.93) | 24 (72.72) | 24(72.72) | ||
| Positive | 9 (27.27) | 2 (6.06) | 9 (27.27) | 9 (27.27) | ||
| Vaginal pH | 4.54 ± 0.46 | 3.93 ± 0.48a | <0.0001 | 4.57 ± 0.47 | 4.59 ± 0.44b | 0.78 |
| Vaginal wet mount test for microscopic investigation of vaginal discharge | ||||||
| KOH slide for hyphae | 1.00 | 1.00 | ||||
| Present | 0 (0) | 0 (0) | 1 (3.03) | 1 (3.03) | ||
| Absent | 33 (100) | 33 (100) | 32 (96.96) | 32 (96.96) | ||
| Normal saline test for trichomonas | 1.00 | 1.00 | ||||
| Absent | 33 (100) | 33 (100) | 33 (100) | 33( 100) | ||
| Present | 0 | 0 | 0 | 0 | ||
| Pus cells (hpf) | <0.001 | 0.93 | ||||
| <10 | 3 (9.09) | 24 (72.72) | 5 (15.15) | 5 (15.15) | ||
| 11–20 | 6 (18.18) | 6 (18.18) | 8 (24.24) | 7 (21.21) | ||
| 21–30 | 21 (63.63) | 2 (6.06) | 15 (45.45) | 14 (42.42) | ||
| >30 | 3 (9.09) | 1 (3.03) | 5 (15.15) | 7 (21.21) | ||
| Pus cells (hpf) | 22.96 ± 8.48 | 8.21 ± 7.85 | <0.001 | 23.15 ± 7.32 | 22.15 ± 8.7 | 0.47 |
| Pap smear | ||||||
| Normal | 4 (12.12) | 20 (60.60) | <0.001 | 4 (12.12) | 8 (24.24) | 0.63 |
| Inflammatory | 22 (66.66) | 11 (33.33) | 22 (66.66) | 18 (54.54) | ||
| BV | 7 (21.21) | 2 (6.06) | 6 (18.18) | 6 (18.18) | ||
| Candidiasis | 0(0) | 0(0)a | 1 (3.03) | 1(3.03)b | ||
Data presented were as follows: no (%) or mean ± SD; aP < 0.0001 considered extremely significant on day 11 from day 0 in the Acacia group; bP > 0.05 considered not significant on day 11 from day 0 in the Placebo group; Tests used were as follows: fisher's exact test and Wilcoxon matched paired test.