Table 2:
Diagnostic accuracy values of radiologic signs in detecting the presence of idiopathic intracranial hypertension.
| Radiologic sign | MRI and MR venography (n=145) IIH present (n=107); absent (n=38) |
CT and CT venography (n=96) IIH present (n=77); absent (n=19) |
||||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity (95% CI) | Specificity (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | |
| Any radiologic feature of IIH | 74.8% (65.8%−82.0%) |
94.7% (82.7%−98.5%) |
14.21 (3.67–54.99) |
0.27 (0.19–0.37) |
61.0% (49.9%−71.2%) |
100.0% (83.2%−100.0%) |
- | 0.39 (0.29–0.52) |
| Optic nerve sheath distension | 31.8% (23.7%−41.1%) |
94.7% (82.7%−98.5%) |
6.04 (1.52–23.93) |
0.72 (0.62–0.84) |
16.9% (10.1%−26.8%) |
100.0% (83.2%−100.0%) |
- | 0.83 (0.75–0.92) |
| Posterior scleral flattening | 24.3% (17.2%−33.3%) |
100.0% (90.8%−100.0%) |
- | 0.76 (0.68–0.84) |
6.5% (2.8%−14.3%) |
100.0% (83.2%−100.0%) |
- | 0.94 (0.88–0.99) |
| Transverse venous sinus stenosis | 53.3% (43.9%−62.4%) |
97.4% (86.5%−99.5%) |
20.24 (2.90–141.17) |
0.48 (0.39–0.59) |
45.5% (34.8%−56.5%) |
100.0% (83.2%−100.0%) |
- | 0.55 (0.44–0.67) |
| Empty or partially empty sella | 29.9% (22.1%−39.2%) |
97.4% (86.5%−99.5%) |
11.36 (1.61–80.33) |
0.72 (0.63–0.82) |
40.3% (30.0%−51.4%) |
100.0% (83.2%−100.0%) |
- | 0.60 (0.50–0.72) |
| Increased tortuosity of optic nerve sheath | 5.6% (2.6%−11.7%) |
100.0% (90.8%−100.0%) |
- | 0.94 (0.90–0.99) |
2.6% (0.7%−9.0%) |
100.0% (83.2%−100.0%) |
- | 0.97 (0.94–1.01) |
| Caudal descent of cerebellar tonsils | 3.7% (1.5%−9.2%) |
100.0% (90.8%−100.0%) |
- | 0.96 (0.93–1.00) |
3.9% (0.8%−11.0%) |
100.0% (83.2%−100.0%) |
- | 0.96 (0.92–1.01) |
| Protrusion of optic nerve head | 3.7% (1.5%−9.2%) |
97.4% (86.5%−99.5%) |
1.42 (0.16–12.32) |
0.99 (0.93–1.05) |
2.6% (0.7%−9.0%) |
100.0% (83.2%−100.0%) |
- | 0.97 (0.94–1.01) |