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. 2022 May 16;7(6):780–795. doi: 10.1038/s41564-022-01121-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — The association for CRC (n = 44) is shown on the left, and for IBD (n = 56) is shown on the right. The black line represents the line of best fit using a linear model and the grey shaded area represents 95% confidence interval. Desparsified lasso was used to obtain 95% confidence intervals (CI) and p-values (pval) for the association. P-values were adjusted for multiple comparisons using Benjamini-Hochberg (FDR) method (padj). CRC: colorectal cancer, UC: Ulcerative colitis, CD: Crohn’s Diseases.