Extended Data Fig. 5. Scatterplots showing correlation between taxa profiles generated from two transformation approaches across three random samples from colorectal cancer cohort.

The x-axis shows taxa profile resulting from one approach, where we summarize taxa ranks, combine summarized rank matrices, and CLR transform the combined matrix (CLR_taxa_combined), and the y-axis represents taxa profiles resulting from the second approach, where we summarize taxa ranks, CLR transform each taxa rank, and combine the CLR-transformed taxa ranks (CLR_taxa_ranks). The black line represents the line of best fit using a linear model. Spearman’s rho and associated two-tailed p-values are shown.