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. 2021 Oct 15;43(6):1473–1483. doi: 10.1038/s41401-021-00786-2

Fig. 1. Effects of SFN on HFD-induced hepatic steatosis and inflammation.

Fig. 1

a Representative livers from the mice fed a ND, a HFD, or HFD + SFN. Scale bar, 10 mm. b Liver weight (left panel) and liver-to-body weight indices (%) (right panel). Representative images of lipid droplets by (c) H&E staining (original magnification, ×200; scale bars, 100 μm) and by (d) oil red O (original magnification, ×100; scale bars, 200 μm). e Content of liver TG (left panel) and TC (right panel). f Levels of plasma ALT (left panel) and AST (right panel). g Levels of plasma TG, TC, LDL and HDL. h Hepatic ELISA levels of IL-1β, TNF-α and MCP-1; i Quantification of the hepatic genes involved in inflammation. n = 8. Data are mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.