Table 2.

Baseline variables independently associated with an acute cerebrovascular event in the derivation cohort.

Variablea	Univariable HR (95% CI)	Multivariable HR (95% CI)
Prior stroke or TIA	2.6 (1.9–3.5)	2.4 (1.8–3.3)
Temperatureb	0.7 (0.6–0.9)	0.8 (0.7–0.9)
History of pulmonary disease	0.6 (0.4–0.9)	0.6 (0.4–0.8)
History of hypertension	2.1 (1.5–3.0)	2.0 (1.4–2.7)
White blood cell countb	1.05 (1.02–1.08)	1.05 (1.02–1.07)
Systolic blood pressurec	1.09 (1.03–1.15)	1.09 (1.03–1.15)

Abbreviations: HR, hazard ratio; CI, confidence interval; TIA, transient ischemic attack.

^aCox regression with 5-fold cross validation was used to identify baseline clinical factors associated with the primary outcome of an acute cerebrovascular event. Factors associated at the univariate level (p<0.10) were then entered into a multivariable Cox regression model. Factors independently associated with the primary outcome at p<0.05 are described herein. Temperature, white blood cell count, and systolic blood pressure were analyzed as continuous variables, while prior stroke or TIA, history of pulmonary disease, and history of hypertension were analyzed as dichotomous variables.

^bTemperature and white blood cell count were analyzed per unit of each.

^cSystolic blood pressure was analyzed per 10 units mmHg.