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. 2022 Jun 2;31(8):106589. doi: 10.1016/j.jstrokecerebrovasdis.2022.106589

Table 3.

CANDLE: a clinical score for stratifying stroke risk among patients hospitalized with COVID-19 Infection.

CANDLE Parameters Multivariable HR (95% CI)
Cerebrovascular disease history 2.5 (1.9–3.4)
Afebrile temperature (<38.3 °C) 2.1 (1.3–3.4)
No pulmonary disease history 1.8 (1.2–2.6)
Disorder of hypertension 1.9 (1.4–2.7)
Leukocytosis (WBC count >11 K/uL) 1.7 (1.2–2.2)
Elevated systolic blood pressure (>140 mm Hg) 1.7 (1.3–2.2)

Abbreviations: HR, hazard ratio; CI, confidence interval; WBC, white blood cell.

aMultivariable Cox regression was used to examine the independent association between baseline clinical parameters and the risk of an acute cerebrovascular event.