TABLE 1.
Toxin | LC50 (ng/cm2)a | Relative toxicityb | Kcom (nM)c |
---|---|---|---|
Cry1Ac | 7.98 (5.04–11.02) | 1 | 3.7 ± 0.8 |
503SS504 | 7.35 (4.67–10.58) | 1.08 | 4.2 ± 0.9 |
506NNI508 | 8.15 (5.68–11.26) | 0.97 | 4.5 ± 1.1 |
509QNR511 | 26.94 (23.48–30.63) | 0.30 | 38.5 ± 5.3 |
522ST523 | 8.93 (6.74–12.15) | 0.89 | 4.6 ± 0.9 |
524ST525 | 8.53 (5.83–11.64) | 0.94 | 4.7 ± 1.1 |
509Q | 17.96 (14.46–21.56) | 0.43 | 18.5 ± 3.5 |
510N | 9.23 (7.21–12.54) | 0.86 | 3.5 ± 0.9 |
511R | 19.84 (16.34–23.14) | 0.40 | 32.5 ± 5.2 |
513Y | 22.81 (18.31–27.21) | 0.35 | 35.5 ± 5.9 |
Ninety-five percent confidence limits are given in parentheses.
Relative toxicity yielded by wild-type toxin LC50/mutant toxin LC50.
Dissociation constant calculated from homologous competition binding assays.