Table 7.
Aggregated findings from meta-analyses for Spetzler-Martin grade III
| Complication | Studies | Events | N patients | % (95%CI) | I2 | τ2 |
|---|---|---|---|---|---|---|
| Complications of embolisation | 3 | 10 | 44 | 22.8 (0–71.6) | 88.3% | 0.15 |
| Leading to deficit | 3 | 6 | 44 | 12.6 (0–50.5) | 82.8% | 0.095 |
| Permanent deficit | 3 | 4 | 44 | 7.48 (0–29.5) | 62.3% | 0.033 |
| Transient deficit | 3 | 2 | 44 | 2.52 (0–20.6) | 61.3% | 0.031 |
| Technical without deficit | 3 | 4 | 44 | 7.01 (0.0954–19.6) | 14.7% | 0.0034 |
| Haemorrhagic | 3 | 5 | 44 | 9.16 (0–52.4) | 87.4% | 0.14 |
| Non-haemorrhagic | 3 | 5 | 44 | 9.18 (0.948–22.1) | 9.95% | 0.0022 |
| mRS > 2 following embolisation | 1 | 1 | 10 | 10 (0–38.1) | N/A | N/A |
| Mortality | 4 | 0 | 54 | 0 (0–3.24) | 0% | 0 |
| Subsequent surgery | 3 | 5 | 44 | 10.6 (2.08–22.8) | 0% | 0 |
| Leading to deficit | 3 | 2 | 44 | 2.99 (0–12.1) | 0% | 0 |
| Permanent deficit | 3 | 2 | 44 | 2.99 (0–12.1) | 0% | 0 |
| Transient deficit | 3 | 0 | 44 | 0 (0–3.73) | 0% | 0 |
| Haemorrhagic | 2 | 0 | 35 | 0 (0–4.45) | 0% | 0 |
| Non-haemorrhagic | 2 | 0 | 35 | 0 (0–4.45) | 0% | 0 |
| Residual AVM post-treatment | 4 | 2 | 54 | 1.94 (0–9.32) | 0% | 0 |
| Infection | 2 | 0 | 35 | 0 (0–4.45) | 0% | 0 |
| Mortality | 4 | 0 | 54 | 0 (0–3.24) | 0% | 0 |
| mRS > 2 following surgery | 3 | 8 | 45 | 12.2 (0.53–31.7) | 48% | 0.018 |
| Blood loss (mean in ml) | 2 | N/A | 13 | 273.5 (98.99–448) | 0% | 0 |
| Operative time (mean in minutes) | 2 | N/A | 13 | 307.2 (111.8–502.5) | 93.8% | 18,632 |
% (95%CI) result from meta-analysis of proportions with 95% confidence interval in parentheses unless otherwise stated, mRS modified rankin scale, AVM arteriovenous malformation, N/A inestimable value