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. 2022 Jun 1;79(6):331. doi: 10.1007/s00018-022-04347-6

Fig. 6.

Fig. 6

Effect of IL-21 administration on IL-21R expression and peripheral immune cells. Mice were given five injections of IL-21 or four injections of anti-IL-21R antibody (IL-21R blocker) and the following were determined. A IL-21R expression in the brain by qPCR; dot plot depict the percentages of cells in the spleen as determined by flow cytometry. B B plasma cells; C Tfh cells; D B1 cells; E MHC-II expression on macrophages