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. 2022 Jun 1;20:84. doi: 10.1186/s43141-022-00370-z

Table 4.

In silico distribution profile of hesperidin as obtained from the AdmetSar server

Distribution substrate/inhibitor Profile
p-gp substrate/inhibitor probability Non-substrate/non-inhibitor
CYP-2C9 substrate/inhibitor Non-substrate/non-inhibitor
CYP-2D6 substrate/inhibitor Non-substrate/non-inhibitor
CYP-3A4 substrate/inhibitor Substrate/non-inhibitor
CYP-1A2 inhibitor Non-inhibitor
CYP-2C19 inhibitor Non-inhibitor
CYP inhibitory promiscuity 0.6670