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. 2022 May 19;9:849902. doi: 10.3389/fnut.2022.849902

FIGURE 2.

FIGURE 2

Representative magnetic resonance imaging data following 12-week consumption of a cranberry extract or a placebo. (A) Axial view of FastSurfer cortical and subcortical segmentations superimposed on a T1-weighted image; (B) axial T2-weighted fluid attenuated inversion recovery (FLAIR) image; (C) a coronal view of the T1-weighted image indicating regions that showed significantly increased perfusion after 12 weeks consumption of a cranberry extract—namely, from superior to inferior, the right caudate nucleus, accumbens area, and entorhinal cortex; (D) an axial cerebral blood flow (CBF) map, in the T1 space, derived from arterial spin labelling data; (E) t-value maps overlaid on a standard brain show trends to increased perfusion in the cranberry group as compared to the placebo group, in similar regions to those indicated in the ROI-wise analyses; and (F) differences in mean blood perfusion for the right caudate nucleus (rCN), right nucleus accumbens (rNAc), and right entorhinal cortex (rEC), with p-values represented for group × time interaction effects between cranberry and placebo groups from baseline to follow-up.