Figure 4.

Density expression of chemokine receptors CXCR3, CCR7 and frequencies of CXCR5 in the CD21^hi subset. (A) Representative histogram of treated LN patients (n=7 responders) to evaluate density expression of CXCR3 between ABCs and CD21^hi subsets. (B) Representative histogram of treated LN patients to evaluate density expression of CCR7 between ABCs and CD21^hi subsets. (C) Representative histogram of a treated LN patient to evaluate density expression of CXCR5 between ABCs and CD21^hi subsets; further comparative analysis of CD21 gMFI of the mentioned subsets. (D) Comparative analysis of CXCR5 frequencies over the CD21^hi subset between patients at the beginning of induction therapy and the same patients after 6 months treated. All comparative analysis were assessed by a Wilcoxon test. *p ≤ 0.05.