Table 1.

Demographics, clinical and laboratory features of SLE/LN patients.

Features	SLE non-LN	LN month 0	LN month 6
Gender - #
Male	2	7	4
Female	8	10	5
Age in years – median	30 (28-32)	26 (20-33)	22 (20-39)
Disease Activity - median
SLEDAI score (min.-max.)	2 (0-6)	22 (16-35)	8 (2-12)
Laboratory Values - median
White blood cell count/mL [106]	5.4 (4.1-5.82)	6.5 (5.45-9.75)	8.0 (4.7-8.8)
Absolute lymphocyte count/mL [106]	1.32 (1.00-1.62)	0.75 (0.48-1.07)	1.12 (0.70-1.74)
Monocytes, %	7.3 (6.8-8.4)	6.3 (4.6-8.8)	8.7 (7.6-9.5)
Neutrophils, %	62.5 (50.7-71.8)	81.1 (74.8-89.1)	72 (64.9-78.9)
Platelet count, K/µL	205 (180-269)	167 (91.5-228)	271 (214-326)
B cells, %	14.7 (10.91-23.78)	22.3 (17.75-24.95)	5.4 (5.05-8.69)
Creatinine, mg/dL	0.6 (0.5-0.7)	2.2 (1.4-3.9)	0.9 (0.6-1.1)
eGFR, mL/min	119 (112-159)	35.4 (27.9-54.8)	107 (74-127)
C3, mg/dL	110 (88.0-118.8)	53 (40.5-60.5)	99 (90.5-120.5)
C4, mg/dL	23.5 (16.7-26.7)	8 (8-12.5)	30 (14.5-38.5)
Anti-dsDNA (UI/mL)	30 (8.3-62.0)	481 (128.1-688.1)	7.9 (4.4-56.9)
Treatments – #
Mycophenolate Mofetil	1	8	5
Cyclophosphamide	–	9	4
Prednisone	2	17	9
Hydroxychloroquine	6	10	6
Chloroquine	1	4	2
Azathioprine	2	1	–
Classification of Lupus Nephritis by ISN/RPS
Class IV	–	2	1
Class III+V	–	2	1
Class IV+V	–	13	7
Outcomes - #
No Remission			2
Partial Remission	–	–	4
Complete Remission	–	–	3
Healthy individuals
Male	4
Female	5
Age in years – median	28 (25-35)
White blood cell count/mL [106]	4.2 (4.1-5.1)
Absolute lymphocyte count/mL [106]	0.81 (0.64-0.92)
B cells, %	7.6 (5.04-11.25)

Data presented are the median (IQR), except for SLEDAI score presented as median (min.-max. values). # represents the number of individuals.