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. 2022 May 19;13:876168. doi: 10.3389/fimmu.2022.876168

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Copyright © 2022 Zhuang, Huang, Zeng, Wu, Qiao, Liu, Wang, Zhou and Xiong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Damage changes in the pancreas at different time points. (A) Pathological observation of pancreas (n = 3,200 × magnification, scale bar = 100 µm; the black arrow represents inflammation infiltration, edema, hemorrhage, and acinar cell necrosis, and the red arrow represents fibrous hyperplasia and granulation tissue). (B) Pancreatic pathological scores from 0 to 5. (C) Serum amylase activity. (D) Pancreatic lipase activity. Data are expressed as the mean ± SD (n = 6). **p < 0.01, ***p < 0.001 compared with the Sham group.