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. 2022 May 19;13:876168. doi: 10.3389/fimmu.2022.876168

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Copyright © 2022 Zhuang, Huang, Zeng, Wu, Qiao, Liu, Wang, Zhou and Xiong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change of immune cells with immunosuppressed rats. (A, B) Measurement of macrophages in the small intestines. (A) Representative images of macrophages for immunohistological staining (200 × magnification, scale bar = 50 µm). (B) Average optical density of macrophages. (C, D) Measurement of dendritic cells in the small intestines. (C) Representative images of dendritic cells for immunohistological staining. (D) Average optical density of dendritic cells. Data are expressed as the mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001 compared with the Sham group; ^##p < 0.01, ^###p < 0.001 compared with the SAP group.