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. 2021 Aug 23;43(6):1544–1555. doi: 10.1038/s41401-021-00757-7

Fig. 1. Comparation of antitumor effects of isopsoralen, osthole, and xanthotoxin on different breast cancer cells.

Fig. 1

a SRB assay was performed to measure the effects of three components on cell viability of breast cancer cells (MDA-MB-231, MDA-MB-231BO, and MCF-7) and normal mammary epithelial MCF-10A cells. b Wound-healing assay was performed to detect the effects of three components (25 μg/mL) on cell migration of MDA-MB-231, MDA-MB-231BO, and MCF-7 breast cancer cells. c Transwell assay was performed to investigate the effects of three components (25 μg/mL) on cell invasion of MDA-MB-231 and MDA-MB-231BO breast cancer cells. Data were expressed as the mean ± SD for triplicate.*P < 0.05, **P < 0.01 vs. the control group for 24 h; #P < 0.05, ##P < 0.01 vs. the control group for 48 h. Amplification factors: 100× for b and 200× for c.