Fig. 8. A proposed model for the cadioprotection of AA in MI heart and OGD cardiomyocytes.
AA modulates mitophagic and glycophagic level in isolated OGD cardiomyocytes and/or MI mice myocardium through the activation of the AMPKα and PI3K/Akt signaling pathways, thereby contributing to the increased energy metabolism and cardioprotection of AA in vivo and in vitro. Red arrows indicate the promotion, and green arrows indicate the reduction.