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. 2021 Sep 14;43(6):1395–1407. doi: 10.1038/s41401-021-00763-9

Fig. 8. A proposed model for the cadioprotection of AA in MI heart and OGD cardiomyocytes.

Fig. 8

AA modulates mitophagic and glycophagic level in isolated OGD cardiomyocytes and/or MI mice myocardium through the activation of the AMPKα and PI3K/Akt signaling pathways, thereby contributing to the increased energy metabolism and cardioprotection of AA in vivo and in vitro. Red arrows indicate the promotion, and green arrows indicate the reduction.