Table 1.
Drugs and compounds targeting survival genes and their correlated targets derived from Targetmine.
| DrugBank interaction protein name | Action Type | DrugBank interaction compound identifier | DrugBank interaction compound name |
|---|---|---|---|
| Tumor necrosis factor ligand superfamily member 11 | Inhibitor | Drug Bank: DB00480 | Lenalidomide |
| Urokinase-type plasminogen activator | Inhibitor | DrugBank: DB00594 | Amiloride |
| Fibrinogen alpha chain | Antagonist | DrugBank: DB00364 | Sucralfate |
| Fibrinogen alpha chain | Antagonist | KEGG DRUG: D00446 | Sucralfate |
| Fibronectin | Cleavage | DrugBank: DB08888 | Ocriplasmin |
| Plasminogen activator inhibitor 1 | Antagonist | DrugBank: DB00197 | Troglitazone |
| Platelet-derived growth factor receptor beta | Antagonist | DrugBank: DB00619 | Imatinib |
| Platelet-derived growth factor receptor beta | Inhibitor | DrugBank: DB12010 | Fostamatinib |
| Mast/stem cell growth factor receptor Kit | Antagonist | DrugBank: DB00619 | Imatinib |
| Mast/stem cell growth factor receptor Kit | Inhibitor | DrugBank: DB12010 | Fostamatinib |
| CCAAT/enhancer-binding protein beta | Inhibitor | DrugBank: DB04216 | Quercetin |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB00213 | Pantoprazole |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB00338 | Omeprazole |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB00448 | Lansoprazole |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB00736 | Esomeprazole |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB01129 | Rabeprazole |
| Potassium-transporting ATPase alpha chain 1 | Inhibitor | DrugBank: DB05351 | Dexlansoprazole |
| Proteinase-activated receptor 1 | Antagonist | DrugBank: DB09030 | Vorapaxar |
| Cathepsin K | Inhibitor | DrugBank: DB06670 | Odanacatib |