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. 2021 Oct 19;43(6):1605–1615. doi: 10.1038/s41401-021-00779-1

Table 1.

The MIC50 activities of the B2 analogues against M. smegmatis.

graphic file with name 41401_2021_779_Taba_HTML.gif
No. R1 R2 MIC50 (μM)
B2 graphic file with name 41401_2021_779_Tabb_HTML.gif graphic file with name 41401_2021_779_Tabc_HTML.gif 0.38
B2a graphic file with name 41401_2021_779_Tabd_HTML.gif graphic file with name 41401_2021_779_Tabe_HTML.gif 2.50
B2b graphic file with name 41401_2021_779_Tabf_HTML.gif graphic file with name 41401_2021_779_Tabg_HTML.gif 1.62
B2c graphic file with name 41401_2021_779_Tabh_HTML.gif graphic file with name 41401_2021_779_Tabi_HTML.gif 6.98
B2d graphic file with name 41401_2021_779_Tabj_HTML.gif graphic file with name 41401_2021_779_Tabk_HTML.gif 5.58
B2e graphic file with name 41401_2021_779_Tabl_HTML.gif >50
B2f graphic file with name 41401_2021_779_Tabm_HTML.gif >50
B2g graphic file with name 41401_2021_779_Tabn_HTML.gif >50
PBTZ169 – – 0.01
TBA-7371 – – 2.31
Rifampin – – 1.09