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. 2022 May 19;12:794170. doi: 10.3389/fcimb.2022.794170

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Copyright © 2022 Wu, Yang, Fan, Guo, Li, Gu, Zhang, Gao, Liu and Yin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Refraction curves based on random extraction of sequencing data from fecal samples from the six subgroups. (B–D) β-diversity analysis conducted with the unweighted unifrac algorithm. Ellipses represent 95% confidence intervals for each subgroup in Figure 3B . *P<0.05. A1, TPOAb-positive women with SCH and no LT₄; A2, TPOAb-positive women with SCH and low-dose LT₄; A3, TPOAb-positive women with SCH and high-dose LT₄; B1, TPOAb-negative women with SCH and no LT₄; B2, TPOAb-negative women with SCH and low-dose LT₄; B3, TPOAb-negative women with SCH and high-dose LT₄.