Table 1.
Demographic and clinical characteristics of patients with glioma with low and high expression of CKS2 in TCGA (n = 670).
| Characteristic | Levels | CKS2 Expression | p | |
|---|---|---|---|---|
| Low (n = 335) | High (n = 335) | |||
| Gender (%) | Female | 143 (21.3%) | 141 (21.0%) | 0.938 |
| Male | 192 (28.7%) | 194 (29.0%) | ||
| Age [median (IQR)] | 39 (31, 49.5) | 54 (39, 63) | <0.001 | |
| Race | Asian | 2 (0.3%) | 11 (1.7%) | 0.125 |
| Black or African American | 12 (1.8%) | 20 (3%) | ||
| White | 315 (47.9%) | 298 (45.3%) | ||
| WHO grade | G2 | 182 (29.7%) | 34 (5.5%) | <0.001 |
| G3 | 117 (19.1%) | 120 (19.6%) | ||
| G4 | 6 (1.0%) | 154 (25.1%) | ||
| Histological type | Astrocytoma | 115 (17.2%) | 77 (11.5%) | <0.001 |
| Glioblastoma | 6 (0.9%) | 154 (23.0%) | ||
| Oligoastrocytoma | 91 (13.6%) | 37 (5.5%) | ||
| Oligodendroglioma | 123 (18.4%) | 67 (10.0%) | ||
| IDH status | WT | 39 (5.9%) | 198 (30%) | <0.001 |
| Mut | 294 (44.5%) | 130 (19.7%) | ||
| 1p/19q codeletion | codel | 109 (16.4%) | 59 (8.9%) | <0.001 |
| non-codel | 225 (33.9%) | 271 (40.8%) | ||
TCGA, The Cancer Genome Atlas database; CKS2, cyclin-dependent kinase regulatory subunit 2.