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. 2022 May 19;13:881453. doi: 10.3389/fimmu.2022.881453

Table 2.

The univariate and multivariate analyses of overall survival according to CKS2 expression, after adjusting for other potential predictors in CGGA (n = 483).

Characteristics Total (N) Univariate Analysis Multivariate Analysis
HR (95% CI) P-value HR (95% CI) P-value
Gender (Male vs. Female) 483 0.979 (0.817–1.174) 0.823
Age (>60 vs. <=60) 483 2.125 (1.619–2.789) <0.001 1.193 (0.901–1.578) 0.218
WHO grade (G3 and G4 vs. G2) 483 4.843 (3.744–6.265) <0.001 3.069 (2.331–4.040) <0.001
IDH status (WT vs. Mut) 483 3.116 (2.591–3.748) <0.001 1.668 (1.362–2.043) <0.001
1p/19q codeletion (non-codel vs. codel) 483 4.410 (3.256–5.973) <0.001 2.849 (2.062–3.934) <0.001
CKS2 (High vs. Low) 483 2.752 (2.279–3.322) <0.001 1.793 (1.473–2.184) <0.001

CKS2, Cyclin-dependent kinase regulatory subunit 2.