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. 2022 May 19;13:881453. doi: 10.3389/fimmu.2022.881453

Table 3.

Hallmark Pathways enriched in high- and low-risk groups by using GSEA.

ID NES P-value p.adjust FDR
HALLMARK_ALLOGRAFT_REJECTION 1.628 0.001 0.004 0.002
HALLMARK_COMPLEMENT 1.461 0.001 0.004 0.002
HALLMARK_E2F_TARGETS 1.986 0.001 0.004 0.002
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION 2.013 0.001 0.004 0.002
HALLMARK_G2M_CHECKPOINT 2.042 0.001 0.004 0.002
HALLMARK_HYPOXIA 1.467 0.001 0.004 0.002
HALLMARK_INFLAMMATORY_RESPONSE 1.576 0.001 0.004 0.002
HALLMARK_INTERFERON_GAMMA_RESPONSE 1.763 0.001 0.004 0.002
HALLMARK_MYC_TARGETS_V1 1.470 0.001 0.004 0.002
HALLMARK_TNFA_SIGNALING_VIA_NFKB 1.641 0.001 0.004 0.002
HALLMARK_APOPTOSIS 1.482 0.001 0.004 0.002
HALLMARK_COAGULATION 1.600 0.001 0.004 0.002
HALLMARK_INTERFERON_ALPHA_RESPONSE 1.670 0.001 0.004 0.002
HALLMARK_IL6_JAK_STAT3_SIGNALING 1.710 0.001 0.004 0.002
HALLMARK_ANGIOGENESIS 1.929 0.001 0.004 0.002
HALLMARK_GLYCOLYSIS 1.436 0.002 0.006 0.004
HALLMARK_KRAS_SIGNALING_UP 1.387 0.002 0.006 0.004
HALLMARK_MITOTIC_SPINDLE 1.364 0.003 0.008 0.005

GSEA, gene set enrichment analysis; NES, normalized enrichment score; FDR, false discovery rate.