Table 3.
Effect of A. mollissima leaves extract on acetic acid-induced writhing of mice (n = 5).
| Animal group | Dose (mg/kg bw) | Mean writhing ± SD | % Inhibition of writhing | t-test (value of p) |
|---|---|---|---|---|
| Negative control | – | 26.4 ± 2.79 | – | – |
| Diclofenac Na | 25 | 8.2 ± 1.64*▲Δ | 68.94 | 12.56 (p < 0.0001) |
| A. mollissima extract | 250 | 16.8 ± 4.49*θ Δ | 36.36 | 4.07 (p = 0.0036) |
| A. mollissima extract | 500 | 12.2 ± 2.16*θ▲ | 53.78 | 8.98 (p < 0.0001) |
* p < 0.05 vs. Control (Dunnett’s t test); θ p < 0.05 vs. diclofenac Na 25 mg/kg bw; ▲ p < 0.05 vs A. mollissima extract 250 mg/kg bw; Δ p < 0.05 vs. A. mollissima extract 500 mg/kg bw (pair-wise comparison by Post Hoc Tukey test).