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. 2022 May 19;13:855810. doi: 10.3389/fpsyt.2022.855810

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Copyright © 2022 Hou, Miao, Meng, Liu, Wang, Tan and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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S-ketamine relieved depression-like behaviors of mice exposed to CUS. (A) Procedure of the experiment 1. (B,C) Motion trail and time of the center zone in OFT (n = 5–8). (D,E) Motion trail and time of the open arms in EPM (n = 5–7). (F,G) Percentage of immobile time in the TST (n = 7–8). (H) Percentage of immobile time in the FST (n = 7–9). The data are expressed as the mean ± standard error, and ^∗P < 0.05.