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. 2022 May 19;9:880553. doi: 10.3389/fmed.2022.880553

Table 3.

Top 10 research foci related to treatment in each 2-years period.

Rank 2012–2013 2014–2015 2016–2017 2018–2019 2020–2021
1 Antibodies, monoclonal Immunosuppressive agents Infliximab Gastrointestinal agents Infliximab
2 Immunosuppressive agents Infliximab Gastrointestinal agents Infliximab Gastrointestinal agents
3 Infliximab Antibodies, monoclonal Immunosuppressive agents Anti-inflammatory agents Anti-inflammatory agents
4 Anti-inflammatory agents Anti-inflammatory agents Anti-inflammatory agents Immunosuppressive agents Remission induction
5 Anti-inflammatory agents, non-steroidal Gastrointestinal agents Remission induction Remission induction Tumor necrosis factor inhibitors
6 Antibodies, monoclonal, humanized Anti-inflammatory agents, non-steroidal Adalimumab Antibodies, monoclonal, humanized Immunosuppressive agents
7 Gastrointestinal agents Remission induction Colectomy Adalimumab Adalimumab
8 Remission induction Antibodies, monoclonal, humanized Antibodies, monoclonal Colectomy Antibodies, monoclonal, humanized
9 Postoperative complications Adalimumab Postoperative complications Postoperative complications Postoperative complications
10 Adalimumab Colectomy Antibodies, monoclonal, humanized Antibodies, monoclonal Colectomy