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. 2022 May 19;13:880878. doi: 10.3389/fphar.2022.880878

FIGURE 1.

FIGURE 1

HO induces NOX4 expression in lung tissue. To determine the role of NOX4 in HALI, wild type (WT) mice (C57BL/6J male, ∼25 g body weight) were exposed to either NO or HO (95% oxygen) for 66 h. Total lung tissue protein was then subjected to SDS-PAGE followed by immunoblotting with anti-NOX4 antibody. (A) HO significantly enhanced the expression of NOX4 as compared to NO (B) Densitometric quantification of NOX4. The data were normalized to GAPDH. n = 4. **p < 0.01.