Table 1.
Baseline characteristics of the patients with primary biliary cholangitis [mean+/-standard deviation/median (range)].
| All (n = 157) | Female (n = 136) | Male (n = 21) | p values (males vs. females) | |
|---|---|---|---|---|
| Age (years) | 54.41 ± 11.38/54.00 (25~80) | 54.19 ± 11.08/54.0 (25~80) | 55.81 ± 13.36/52.0(36~77) | 0.546 |
| AMA (diluted titer)* | 410.8 ± 474.9/160.0 (0~1280) | 387.9 ± 461.4/160.0 (0~1280) | 560.0 ± 545.8/320 (0~1280) | 0.142 |
| ANA (diluted titer)* | 480.7 ± 556.8/160.0 (0~1280) | 499.0 ± 558.0/320.0 (0~1280) | 335.3 ± 546.4/0 (0~1280) | 0.32 |
| AST(U/L) | 98.63 ± 74.47/83.5 (14~511) | 98.73 ± 74.42/85.0 (14~488) | 98.0 ± 102.7/68.0 (15~511) | 0.969 |
| ALT(U/L) | 99.49 ± 98.43/79.0 (9~978) | 94.60 ± 70.80/85.0 (14~488) | 130.2 ± 198.9/87 (19~978) | 0.124 |
| Alk-p (U/L) | 341.1 ± 221.1/302 (57~1341) | 343.8 ± 229.5/303 (57~1341) | 323.6 ± 160.1/272 (123~670) | 0.704 |
| γ-GT (U/L) | 328.9 ± 324.1/229 (13~2306) | 322 ± 329.9/226(13~2306) | 382.6 ± 278.6/306 (100~1065) | 0.483 |
| Total bilirubin (mg/dL) | 2.66 ± 4.89/1.2 (0.3~46.4) | 2.81 ± 5.46/1.1 (0.2~48.6) | 2.72 ± 1.74/2.6 (0.5~6.5) | 0.941 |
| Albumin (g/dL) | 4.03 ± 0.598/4.10 (2~5) | 4.0 ± 0.493/4.0 (2~5) | 4.23 ± 0.6/4.27 (3~5) | 0.127 |
| eGFR (ml/min/1.73m2) | 89.63 ± 47.67/80.33 (12~179) | 93.53 ± 45.57/86.62 (27~179) | 89.88 ± 50.23/70.2 (12~101) | 0.096 |
| Platelet (K/uL) | 206.7 ± 84.8/190.5 (24~403) | 207.5 ± 88.8/193.5 (24~403) | 202.2 ± 59.9/182.5 (123~301) | 0.845 |
| AFP (ng/mL) | 3.88 ± 1.96/3.00 (1~14) | 3.85 ± 1.87/3.0 (1~14) | 4.03 ± 2.45/3.0 (2~13) | 0.711 |
| Liver cirrhosis, n (%) | 51 (32.5) | 44 (32.5) | 7 (33.3) | 0.929 |
AMA, antimitochondrial antibody; ANA, antinuclear antibody; AST, aspartate transaminase; ALT, alanine aminotransferase; Alk-p, alkaline phosphatase; γ-GT, gamma-glutamyltransferase. eGFR, estimated glomerular filtration rate; AFP, alpha fetoprotein; *, The diluted titer “1, X” was presented as “X”, and the mean+standard deviation/median (range) of X was shown in the table. For example, the diluted titers such as 1,40, 1,80, 1,160, 1,320, 1,640, 1,1280 were presented as 40, 80, 160, 320, 640 and 1280, respectively.