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. 2022 May 19;13:807380. doi: 10.3389/fendo.2022.807380

Table 4.

Incidence of cardiometabolic comorbidities among Chinese boys with obesity assessed between 2008 and 2017 in Hangzhou (Zhejiang Province, China).

Boys Aged <10 years Aged ≥10 years
2008–2012 2013–2017 p-Value 2008–2012 2013–2017 p-Value
N 298 325 600 731
Impaired fasting glucose 59 (20.1%) 95 (29.2%) 0.009 132 (22.1%) 195 (26.7%) 0.055
Impaired glucose tolerance 38 (12.9%) 44 (13.5%) 0.91 76 (12.8%) 124 (17.0%) 0.037
Abnormal glycaemia 78 (26.5%) 127 (39.1%) 0.001 174 (29.1%) 276 (37.8%) 0.001
Type 2 diabetes 1 (0.3%) 4 (1.2%) 0.38 9 (1.5%) 36 (4.9%) 0.001
Hypertension 84 (28.4%) 156 (48.0%) <0.0001 158 (26.5%) 262 (35.8%) <0.0001
Dyslipidaemia 105 (35.4%) 79 (24.5%) 0.004 253 (42.4%) 247 (34.2%) 0.002
Hyperuricaemia 14 (4.7%) 18 (5.6%) 0.72 125 (21.2%) 156 (21.5%) 0.95
Acanthosis nigricans 176 (61.5%) 236 (72.8%) 0.003 414 (69.3%) 518 (70.9%) 0.59
Abnormal liver function 191 (65.0%) 167 (52.2%) 0.001 393 (68.0%) 573 (78.6%) <0.0001
NAFLD 155 (52.2%) 158 (48.6%) 0.38 434 (73.4%) 500 (68.8%) 0.07
Metabolic syndrome 222 (37.0%) 293 (40.1%) 0.26

Data are n (%). p-Values are derived from Fisher’s exact tests, and correspond to comparisons in the incidence of a particular comorbidity between time periods within a given age group. Statistically significant p-values (<0.05) are shown in bold.

NAFLD, non-alcoholic fatty liver disease.