Figure 6.

Topography of hydrogels regulates immune cell response. (a) Representative phase contrast images of human monocyte-derived macrophages cultured on TCP controls and GelMA micropatterns: G, microgrooves/ridges; P, micropillars; U, unpatterned for 3 days. Scale bar, 100 µm. Adapted with permission from Ref. [43]. (b–d) Cellular scaffolds with ICC topography. Scanning electron microscopy image of colloidal crystals made from 110-µm polystyrene beads (b), and ICC scaffolds from silicate gel (c). (d) ICC scaffolds after 5 days in culture with BM stromal cells. Adapted with permission from Ref. [100].