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. 2022 May 19;13:884693. doi: 10.3389/fneur.2022.884693

Table 1.

Statistical feature comparison between the two outcome groups.

Features mRS-90 ≤ 2 (n = 101) mRS-90 > 2 (n = 192) P-value
Clinical features
Age, median (IQR) 63 (51–74) 75 (63–84) <0.0001
Sex 0.016
   Female, n (%) 39 (39%) 104 (54.2%)
   Male, n (%) 62 (61%) 88 (45.8%)
NIHSS score, median (IQR) 13 (7–18) 18 (13–22) <0.0001
Time to admission, median (IQR) 107 (68–186) 135 (68–302) 0.107
Imaging features
Occlusion side 0.017
   Right, n (%) 57 (56%) 79 (41%)
   Left, n (%) 44 (44%) 113 (59%)
Occlusion location 0.280
   ICA Terminus, n (%) 25 (25%) 55 (29%)
   M1, n (%) 50 (49%) 99 (51%)
   M2, n (%) 25 (25%) 34 (18%)
   M3, n (%) 1 (1%) 4 (2%)
e-ASPECTS, median (IQR) 9 (8–10) 9 (7–10) 0.002
Acute ischemic Volume (mL), median (IQR) 9.14 (5–20) 12.52 (5–28) 0.047
Non-acute ischemic volume (mL), median (IQR) 0.39 (0–0) 0.50 (0–1) 0.040
Local acute ischemic volume
M1 (mL), median (range) 0.0 (0.0–9.5) 0.0 (0.0–13.7) 0.006
M2 (mL), median (range) 0.3 (0.0–8.8) 0.8 (0.0–18.8) 0.005
M3 (mL), median (range) 0.0 (0.0–12.5) 0.4 (0.0–20.2) 0.002
M4 (mL), median (range) 0.0 (0.0–7.5) 0.0 (0.0–11.7) 0.004
M5 (mL), median (range) 0.8 (0.0–17.9) 1.3 (0.0–32.0) 0.034
M6 (mL), median (range) 0.1 (0.0–23.0) 0.8 (0.0–25.3) 0.012
Caudate (mL), median (range) 0.0 (0.0–2.6) 0.0 (0.0–2.6) 0.540
Insula (mL), median (range) 0.0 (0.0–8.0) 4.7 (0.0–8.0) 0.201
Internal capsule (mL), median (range) 0.0 (0.0–4.7) 0.0 (0.0–4.8) 0.744
Lentiform (mL), median (range) 2.3 (0.0–5.8) 2.6 (0.0–5.8) 0.679
Brain volume (L), mean (±SD) 1.30 (±0.16) 1.26 (±0.15) 0.043
Cortical CSF volume (%), median (IQR) 6.16 (4–9) 8.7 (6–10) <0.0001
Lateral ventricle volume (%), median (IQR) 2.4 (1–3) 3.4 (2–5) <0.0001
Circulation deficit volume, median (IQR) 15.8 (1–36) 30.42 (6–54) 0.001
CTA CS score, median (IQR) 3.0 (2–3) 2.0 (1–3) <0.001