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. 2022 May 19;13:876253. doi: 10.3389/fgene.2022.876253

FIGURE 3.

FIGURE 3

Screening out the hub gene NAP1L1, and NAP1L1 was up-regulated in HCC. (A) The identification of the 2,145 overlapping DEGs ground on GSE14520, GSE76427, ICGC, and TCGA. (B) The identification of the 101 overlapping survival-related genes ground on GSE76427 and TCGA. (C) The identification of the 33 common genes. (D) The PPI network was constructed using the 33 common genes. (E) The PPI network of the top 10 hub genes via DMNC. (F) The PPI network of the top 10 hub genes via ClusteringCoefficient. (G) The expression of NAP1L1 applying the Oncomine database. (H) The expression of NAP1L1 applying the TIMER database (*p < 0.05; **p < 0.01; ***p < 0.001). (I) The expression of NAP1L1 applying the HPA database. (J) The mRNA expression of NAP1L1 applying the RT-qPCR.