Table 2. Relative Reduction of 5-Year Death Risk Associated With the Optimal Policy Tree (OPT) Optimal Margins as Calculated in the Patients With KRAS-Variant Tumors.

Node	Mean predicted probability of death (%)
	No. of patients	10.0 mm	7.0 mm	5.0 mm	3.0 mm	1.0 mm	0.5 mm	0.0 mm	RRR (%)
Train data set (n = 302)
3	117	63.89	63.66	64.12	66.68	67.43	68.85	72.84	12.60
4	54	55.24	54.95	55.17	56.19	57.05	58.41	63.21	13.06
6	78	65.42	65.56	66.07	67.76	68.65	69.89	73.31	10.57
7	53	64.44	64.33	64.94	66.90	67.74	69.10	72.90	11.75
External validation data set (n = 375)
3	102	57.10	56.60	57.52	57.17	57.35	58.26	60.83	6.95
4	85	56.14	55.79	56.82	56.55	56.69	57.52	60.03	7.06
6	76	63.65	63.38	64.26	64.06	64.24	64.91	67.26	5.76
7	112	58.47	57.92	58.60	58.18	58.34	59.07	61.47	5.77

Abbreviation: RRR, relative risk reduction.