Table 3. Patient Characteristics in the External Cohort.
| Variable | Entire external cohort (n = 878) | |
|---|---|---|
| KRAS variant | Wild type | |
| Entire (n = 375) | Entire (n = 503) | |
| Numerical features, median (IQR) | ||
| Age, y | 61.0 (53.0-70.0) | 61.0 (52.0-69.0) |
| No. of CRLM | 2.0 (1-3) | 2.0 (1-4) |
| Diameter of largest CRLM, cm | 3.0 (2.0-4.0) | 3.0 (2.0-4.2) |
| Margin width, mm | 5.0 (1-10) | 4.0 (1-10) |
| Categorical variables total, No. (%) | ||
| Sex | ||
| Male | 218 (58.1) | 295 (58.6) |
| Female | 157 (41.9) | 208 (41.4) |
| Primary tumor side | ||
| Left | 95 (25.3) | 179 (35.6) |
| Right | 197 (52.5) | 207 (41.2) |
| Rectum | 83 (22.1) | 117 (23.3) |
| Primary tumor (T) stage | ||
| T0-2 | 77 (20.5) | 93 (18.5) |
| T3-4 | 298 (79.5) | 410 (81.5) |
| Primary tumor nodal status | ||
| Yes | 197 (52.5) | 343 (68.2) |
| No | 178 (47.5) | 160 (31.8) |
| Bilobar CRLM | ||
| Yes | 104 (27.7) | 182 (36.2) |
| No | 271 (72.3) | 321 (63.8) |
| Extrahepatic disease | ||
| Yes | 31 (8.3) | 66 (13.1) |
| No | 344 (91.7) | 437 (86.9) |
| Prehepatectomy chemotherapy | ||
| Yes | 293 (78.1) | 398 (79.1) |
| No | 82 (21.9) | 105 (20.9) |
| Intraoperative ablation | ||
| Yes | 38 (10.1) | 36 (7.2) |
| No | 337 (89.9) | 467 (92.8) |
| Positive margin | ||
| Yes | 51 (13.6) | 92 (18.3) |
| No | 324 (86.4) | 411 (81.7) |
Abbreviation: CRLM, colorectal cancer liver metastases.