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Serum IL-1β and TNF-α of MIA-induced KOA rats in each group at days 7 and 14. (A) Serum IL-1β at day 7 after KOA induction. (B) Serum TNF-α at day 7 after KOA induction. (C) Serum IL-1β at day 14 after KOA induction. (D) Serum TNF-α at day 14 after KOA induction. Data are presented as the mean ± SD (n = 5). # p < 0.05, ## p < 0.01 vs. Ctrl group; *p < 0.05 vs. model group.
