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. 2022 May 19;13:882304. doi: 10.3389/fphar.2022.882304

TABLE 1.

Mankin Score—scoring standard of articular pathology (Supplementary Material).

Classification Score
Structure
 Normal 0
 Surface damage 1
 Pannus and surface damage 2
 Shallow fissures formed reach moving layers 3
 Locally reaching the fracture of the bone radiation layer 4
 Reach the weight-bearing area of cartilage defect in the calcified layer of deep bone 5
 Full-thickness cartilage defect 6
Cell
 Normal 0
 Excessive and disordered cells 1
 Cell clustering 2
 Less cells 3
Safranin fast green staining normal
 Normal 0
 Mild dyeing 1
 Medium dyeing 2
 Deep dyeing 3
 Loss of dyeing 4
Integrity of tidal line
 Complete 0
 Incomplete 1
 Incomplete blood vessels pass through 2
 Aggregate score 0–14