Table 1.

Study Population Demographic and Drinking Characteristics

	No. (%)
Characteristic	Total (n=68)		Gabapentin (n=37)		Placebo (n=31)		p valuea
Age, mean (SD), y	49.3	10.6	49.6	10.4	48.9	10.9	0.78
PTSD (current or past)	18	26.5%	9	24.3%	9	29.0%	0.66
Nicotine use	31	45.6%	17	45.9%	14	45.2%	0.95
Antidepressant use	18	26.5%	9	24.3%	9	29.0%	0.66
Sex (male)	50	73.5%	28	75.7%	22	71.0%	0.66
Married/cohabitating	29	42.6%	19	51.4%	10	32.3%	0.11
Education (≤ 12 y)	8	11.8%	5	13.5%	3	9.7%	0.62
Employed	49	72.1%	26	70.3%	23	74.2%	0.72
Race (white)	65	95.6%	35	94.6%	30	96.8%	0.66
Alcohol use and severity indicators, mean (SD)
Drinks per dayb	11.0	4.6	10.8	4.3	11.2	5.0	0.77
Drinks per drinking dayb	13.0	4.8	13.2	4.9	12.8	4.8	0.72
Days abstinent, %b	14.1%	21.3%	14.9%	22.7%	13.3%	19.8%	0.76
Heavy drinking days, %b	83.0%	22.3%	82.8%	23.6%	83.2%	21.0%	0.94
Days abstinent prior to randomization	4.2	2.0	4.2	2.1	4.2	1.9	0.97
Alcohol Dependence Scalec	18.6	7.5	19.7	7.8	17.4	7.1	0.22
OCDSd	27.4	9.4	27.9	9.1	26.7	9.9	0.62
Alcohol Withdrawal Symptom Checkliste	10.5	7.0	10.9	7.4	9.9	6.4	0.53
DSM-5 alcohol withdrawal items positive	4.5	1.3	4.7	1.1	4.4	1.5	0.36
CIWA	2.8	1.8	2.8	2.0	2.8	1.6	0.95
Past alcohol:
Treatments	19	27.9%	13	35.1%	6	19.4%	0.15
Detoxifications	9	13.2%	7	18.9%	2	6.5%	0.13
Alcohol blood tests (biomarkers)
%dCDT≥1.7	50	74.6%	26	72.2%	24	77.4%	0.63
GGT > 36 U/L	52	76.5%	29	78.4%	23	74.2%	0.69

Abbreviations: PTSD, Posttraumatic Stress Disorder; DSM-5, Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition); GGT, y-glutamyltransferase; OCDS, Obsessive Compulsive Drinking Scale; %dCDT, percentage of disialo carbohydrate-deficient transferrin.

^aThe χ² statistic was used for all the categorical variables, and the ANOVA statistic was used for all the continuous variables.

^bCalculated using the 90 days prior to screening.

^cRange, 0–47.

^dRange, 0–56.