Table 2.
Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|
Variables | HR (95% CI) | p | HR (95% CI) | p | |
Sex | Female | Ref | |||
Male | 0.83 (0.40–1.72) | 0.622 | |||
Age (years) | <70 | Ref | |||
≥70 | 1.21 (0.42–3.48) | 0.719 | |||
BMI (kg/m2) | <25 | Ref | |||
≥25 | 0.56 (0.21–1.48) | 0.245 | |||
CEA (ng/ml) | <5 | Ref | |||
≥5 | 0.59 (0.26–1.33) | 0.205 | |||
Tumor location | Right colon | Ref | |||
Left colon | 1.72 (0.73–4.03) | 0.21 | |||
Complications | No | Ref | |||
Yes | 1.11 (0.45–2.73) | 0.812 | |||
Histological grade | G1 and G2 | Ref | |||
G3, etc. | 1.03 (0.39–2.72) | 0.939 | |||
LVI | Absent | Ref | Ref | ||
Present | 2.71 (1.27–5.80) | 0.009 | 2.60 (1.21–5.55) | 0.013 | |
No data | 1.81 (0.23–14.03) | 0.569 | 1.36 (0.17–10.57) | 0.766 | |
LN numbers | <12 | Ref | |||
≥12 | 1.51 (0.20–11.12) | 0.684 | |||
Stage | II | Ref | |||
III | 2.55 (0.60–10.73) | 0.201 | |||
MSI | MSS/MSI‐low | Ref | |||
MSI‐high | 1.18 (0.26–5.30) | 0.822 | |||
No data | 1.29 (0.60–2.77) | 0.502 | |||
f_wt | Continuous | 0.095 (0.0007–12.16) | 0.342 | ||
f_im200 | Continuous | 0.003 (0.0001–0.14) | 0.002 | 0.004 (0.0001–0.15) | 0.0028 |
CEA, carcinoembryonic antigen; LN, lymph node; MSS, microsatellite stable; Ref, reference.