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. 2022 Apr 28;8(4):327–339. doi: 10.1002/cjp2.273

Table 2.

Univariate and multivariate analyses associated with PFS in the Yonsei dataset (n = 180)

Univariate analysis Multivariate analysis
Variables HR (95% CI) p HR (95% CI) p
Sex Female Ref
Male 0.83 (0.40–1.72) 0.622
Age (years) <70 Ref
≥70 1.21 (0.42–3.48) 0.719
BMI (kg/m2) <25 Ref
≥25 0.56 (0.21–1.48) 0.245
CEA (ng/ml) <5 Ref
≥5 0.59 (0.26–1.33) 0.205
Tumor location Right colon Ref
Left colon 1.72 (0.73–4.03) 0.21
Complications No Ref
Yes 1.11 (0.45–2.73) 0.812
Histological grade G1 and G2 Ref
G3, etc. 1.03 (0.39–2.72) 0.939
LVI Absent Ref Ref
Present 2.71 (1.27–5.80) 0.009 2.60 (1.21–5.55) 0.013
No data 1.81 (0.23–14.03) 0.569 1.36 (0.17–10.57) 0.766
LN numbers <12 Ref
≥12 1.51 (0.20–11.12) 0.684
Stage II Ref
III 2.55 (0.60–10.73) 0.201
MSI MSS/MSI‐low Ref
MSI‐high 1.18 (0.26–5.30) 0.822
No data 1.29 (0.60–2.77) 0.502
f_wt Continuous 0.095 (0.0007–12.16) 0.342
f_im200 Continuous 0.003 (0.0001–0.14) 0.002 0.004 (0.0001–0.15) 0.0028

CEA, carcinoembryonic antigen; LN, lymph node; MSS, microsatellite stable; Ref, reference.