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. 2022 May 19;10:876151. doi: 10.3389/fbioe.2022.876151

FIGURE 2.

FIGURE 2

sEVs-derived oncogenic ncRNAs mediate formation of the pre-metastatic niche of ovarian cancer by local stromal remodeling, immunosuppression and evasion, and angiogenesis. sEVs, small extracellular vesicles; EMT, epithelial–mesenchymal transition; MMT, mesothelial–mesenchymal transition; Tregs, regulatory T cells; Th17 cells, T helper 17 cells.