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. 2022 Apr 20;2(2):100160. doi: 10.1016/j.xops.2022.100160

Table 1.

SD-OCT GA at 1- and 2-Year Intervals


Node
1-Year Interval
2-Year Interval
N
Count
GA
Count (%)
OR (95% CI) P
Value
N
Count
GA
Count (%)
OR(95% CI) P
Value
A 372 4 (1) 0.08 (0.03–0.23) <0.01 330 7 (2) 0.14 (0.06–0.32) <0.01
B 272 16 (6) 0.78 (0.43–1.41) 0.41 165 8 (5) 0.55 (0.25–1.21) 0.14
C 9 0 (<33) - - 26 0 (<12) - -
D 19 6 (32) 6.80 (2.48–18.62) <0.01 19 9 (47) 13.52 (5.19–35.27) <0.01
E 24 0 (<12.5) - - 31 3 (10) 1.35 (0.39–4.61) 0.64
F 105 18 (17) 3.58 (1.97–6.52) <0.01 28 10 (36) 8.45 (3.64–19.61) <0.01
G 28 8 (29) 6.07 (2.55–14.47) <0.01 11 0 (<27) - -
H 8 6 (75) 44.83 (8.83–227.60) <0.01 18 10 (56) 19.36 (7.21–51.96) <0.01
Total 837 58 (7) 628 47 (7)

CI = confidence interval; GA = geographic atrophy; OR = odds ratio; SD-OCT = spectral-domain OCT.

Proportions in cells with a count of zero (out of N observations) are estimated using the Rule of 3 whereby the 95% CI for the proportion (%) is between 0 and 3/N.