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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: Clin Cancer Res. 2022 May 13;28(10):2094–2109. doi: 10.1158/1078-0432.CCR-21-3570

Figure 4. HNCAF-0 and HNCAF-1 have contrasting prognostic associations.

Figure 4.

A) Kaplan-Meier plot of HNCAF-0 Protein Activity Gene Set Enrichment among TCGA dataset of head and neck squamous cell carcinoma patients in association with overall survival time, limited to patients with under 10 years of follow-up. Enrichment scores were binarized by log-rank maximization to “high HNCAF-0” and “low HNCAF-0” and showed significant association with improved survival (p=0.0095, median survival time = 602 days vs 1671 days). Hazard ratio is shown below the plot, with 95% confidence interval. B) Kaplan-Meier plot of HNCAF-1 Protein Activity Gene Set Enrichment among TCGA head and neck squamous cell carcinoma patients in association with overall survival time, limited to patients with under 10 years of follow-up, as in A. HNCAF-1 enrichment shows significant association with worse survival (p=0.0041, median survival time = 1718 days vs 773 days). Hazard ratio is shown below the plot, with 95% confidence interval.