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. 2022 Jun 1;13:24. doi: 10.1186/s13229-022-00502-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — POGZ recruits esBAF/BRG1 to neural progenitor genes. A Pie chart showing the overlap of POGZ and BRG1 peaks. B Metaplot of POGZ and BRG1 enrichment (normalized per million mapped reads) across active enhancers (H3K4me1/H3K27ac). C Metaplot of POGZ and BRG1 enrichment (normalized per million mapped reads) across poised enhancers (H3K4me1/H3K27me3). A 6 kb window centered on the peak midpoint was shown. D Heat map view for distribution of POGZ, BRG1, BAF155 and SS18 signals in a ± 3 kb regions across sites bound by POGZ (n = 16,728). E Pie chart showing the overlap of POGZ and BRG1 target genes. F KEGG terms of POGZ⁺ BRG1⁺ genes. G GO terms of POGZ⁺ BRG1⁺ genes. H ChIP-PCR results showing BRG1 enrichment at promoter and enhancer regions of the indicated genes in day 5 neurospheres from control and Pogz−/− ESCs