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. 2022 Jun 2;22:464. doi: 10.1186/s12884-022-04777-x

Fig. 5.

Fig. 5

Interrupted time-series analysis of use of antiemetics while hospitalized for hyperemesis gravidarum 2002–2019. Percentage admitted to Haukeland University Hospital using (a) metoclopramide, (b) prochlorperazine, and (c) any antiemetic while hospitalized. Predicted line visualizes linear trend pre-intervention in 2014 with slope corresponding to yearly change (β1); vertical line illustrating level change in 2014 at the time of treatment guideline update (β2); predicted line after 2014 representing post-intervention trend (β1 + β3) applying Newey-West standard errors to adjust for first order autocorrelation