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. 2022 Jun 1;22:599. doi: 10.1186/s12885-022-09567-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Protein-Protein interaction network: A Diagram showing the network of the BARD1 interaction pattern with partners proteins generated by STRING. B The BARD1-Proteins interaction map showing different degrees of correlation strength by bcGenExMiner. C Pearson’s pairwise correlation graph shows high degree of positively correlated interaction between BARD1 and BLM genes, r = 0.54 and P < 0.0001 in breast cancer patients (4712), by bcGenExMiner. Source: Retrieval of Interacting Genes/Proteins database (STRING v10.5) (https://string-db.org/) [59]. Database of The Breast Cancer Gene-Expression Miner v4.8 (bcGenExMiner v4.8) (http://bcgenex.ico.unicancer.fr/BC-GEM/GEM-Accueil.php?js=1) [61]