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The utility of patient-derived xenograft (PDX) models in gastric cancer research. The gastric cancer tissue or cells of the surgically resected patient was directly implanted into immunodeficient mice, and the fidelity of the model was analyzed. The GCPDX model can be used for biomarker development or novel drug evaluation, etc. Promising candidates may enter clinical trials for evaluation to determine the optimal treatment for patients, enabling personalized medicine.
